Where are mesothelial cells most commonly found?

Mesothelial cells are specialized epithelial cells that line the serous cavities of the body. These cells form a protective layer over internal organs and are crucial in facilitating the movement of these organs by producing a lubricating fluid. The primary locations where mesothelial cells are found include the pleura (lining the lungs), peritoneum (lining the abdominal cavity), and pericardium (surrounding the heart), all of which are classified as serous cavities.

In contrast, while mesothelial cells play a role in structures such as the lungs or gastrointestinal tract, their primary association is with these serous cavities, which specifically require the protective and lubricating functions provided by mesothelial cells. The skin does not contain mesothelial cells because it is lined by a different type of epithelial tissue that serves distinct functions, including protection and sensation. Understanding the specific roles and locations of mesothelial cells emphasizes their importance in body cavities that require a moist and frictionless environment for organ movement.